It Does A Body Bad
Posted by pozlife on November 29, 2006
Crystal use can begin a chain reaction that can take users past the point of no return
By Bob Adams
Crystal meth use can cause two key bodily changes and lead to one significant behavioral change that speeds development of drug resistance.
Cellular Death: Meth use can stimulate the secretion of a protein called tumor necrosis factor, which triggers CD4 cells to self-destruct. HIVers already have higher levels of tumor necrosis factor than uninfected individuals.
Metabolism: Meth can cause anti-HIV drugs to be eliminated from the bloodstream too quickly. HIV can easily mutate resistance against the low levels of drugs that remain in the bloodstream.
Adherence: Meth use can lead to missed antiretroviral doses, which in turn can lead to drug resistance and treatment failure.